Mouse Monoclonal Antibody to Human RPSA(Cat#: RIJL-0225-JL65)
This product is an anti-human RPSA monoclonal antibody generated from the mouse. The antibody can be used for WB, IP, IHC(P), IF and ELISA.
SPECIFIC INQUIRY
Summary
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Description
|
This product is an anti-human RPSA monoclonal antibody generated from the mouse. The antibody can be used for WB, IP, IHC(P), IF and ELISA. |
Product Property
Host Animal |
Mouse |
Species Reactivity |
Human |
Immunogen |
Human RPSA |
Specificity |
This antibody reacts with human RPSA. |
Clonality |
Monoclonal |
Isotype |
IgM |
Type |
Primary Antibody |
Conjugation |
Unconjugated; FITC; PE |
Applications |
WB; IP; IHC(P); IF; ELISA |
Formulations & Storage
Format |
Liquid |
Buffer |
Gelatin, NaN₃ & PBS |
Purity |
>90% |
Storage |
Store at -20°C. |
Target
Alternative Names |
LAMR1; Laminin Receptor 1; Colon Carcinoma Laminin-Binding Protein; Ribosomal Protein SA; 37LRP; Laminin-Binding Protein Precursor P40; 40S Ribosomal Protein SA |
Gene ID |
3921 |
UniProt ID |
P08865 |
Introduction |
RPSA protein, encoded by the RPSA gene in humans, serves dual roles as both a ribosomal protein and a cell surface receptor for laminin. In particular, it plays a pivotal role in various pathogenic processes. The RPSA gene encodes a multifaceted protein that not only functions as a ribosomal component but also acts as a high-affinity, non-integrin laminin receptor. The amino acid sequence of RPSA has remained highly conserved throughout evolution, hinting at its crucial biological function. Notably, studies have shown that the level of RPSA transcripts is elevated in colon carcinoma tissue and lung cancer cell lines compared to their normal counterparts. |
Relevant Pathways |
MAPK signaling pathway |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.