Services

In recent years, as one of the important components of biological life processes, ribosomes have become a hot spot in the field of biology. With experienced scientists and perfect experimental techniques, Creative Biolabs has successfully developed a series of ribosome isolation and analysis solutions to provide our global customers with fast, high-quality, and convenient ribosome services.

Background

Introduction to Ribosomes

Ribosomes are complex molecular machines that exist in all living cells. Ribosomes are at the core of translation in all living organisms. The translation is an important process in life activities and a key step in gene expression, which converts the genetic information carried by messenger RNA (mRNA) into polypeptides or proteins with specific structures and functions. In general, the main functions of ribosomes include decoding information and forming peptide bonds. The two functions reside in two ribonucleoprotein particles (RNPs) of different sizes, which are also known as ribosomal subunits. Each subunit consists of ribosomal protein (r-protein) and ribosomal RNA (rRNA). The small subunit has a decoding function while the large subunit is responsible for catalyzing the formation of peptide bonds.

Fig. 1 Examples of the electron density maps of the 80S ribosome translocation intermediate complex.¹

Importance of Ribosomes

Ribosomes provide the basis for protein production, which drives cell growth. Transcription of ribosomal RNA is closely related to cellular energy state and the production of ribosomal proteins. Ribosomal biogenesis has been implicated in a variety of diseases, especially cancer and hematologic diseases. In addition, studies have shown that ribosomes are also linked to aging. Exploring the structure of ribosomes and related factors will be beneficial to further clarify the molecular mechanism behind these connections.

Our Service

After years of practice and accumulation, Creative Biolabs has successfully completed many ribosome-related projects. With advanced technology, we provide diverse ribosome-related services. Our services include but are not limited to:

• Ribosome Separation and Extraction Services
• Ribosome Analysis Services
• Ribosomal Marker Antibody Development Services

Highlights

• Professional team

Our scientists have excellent theoretical knowledge and extensive experimental experience dedicated to ribosome isolation and analysis.

• Extensive biological sample types

We accept a wide range of biological samples, including tissues and cells. Sample sources include humans, animals, plants, and microorganisms.

• Professional bioinformatics analysis

We have a professional bioinformatics analysis technical team as well as complete hardware equipment, analysis tools, and data analysis charters.

• One-stop service

We provide convenient and fast one-stop ribosome isolation and analysis services to advance your project.

FAQs

Resource

Ribosome Analysis - Creative Biolabs Ribosome Analysis - Creative Biolabs

Creative Biolabs provides comprehensive ribosome services, from initial ribosome isolation and library preparation to final data analysis and interpretation. Leveraging the unparalleled experience and expertise of our world-class team of molecular biologists and bioinformaticians, we can help you achieve satisfactory results quickly. We also provide custom services to meet your project needs. If you are interested, please contact us for more information and a detailed quotation.

Reference

1. Djumagulov, Muminjon, et al. "Accuracy mechanism of eukaryotic ribosome translocation." Nature 600.7889 (2021): 543-546.