Recombinant Protein of Human MRPS18B, aa 1-258(Cat#: RIJL-0225-JL500)
This product is a recombinant human MRPS18B protein with N-terminal His-IF2DI Tag or N-terminal GST Tag. It is availible for WB and ELISA.
Summary
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Description
|
This product is a recombinant human MRPS18B protein with N-terminal His-IF2DI Tag or N-terminal GST Tag. It is availible for WB and ELISA. |
Product Property
| Species Reactivity |
Human |
| Molecule Mass |
50.0 kDa |
| Purity |
>90% determined by SDS-PAGE |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Expression Host |
E.coli |
| Formulation |
10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4 |
| Residues |
1-258aa |
| Sequence |
MAASVLNTVLRRLPMLSLFRGSHRVQVPLQTLCTKAPSEEDSLSSVPISPYKDEPWKYLESEEYQERYGSRPVWADYRRNHKGGVPPQRTRKTCIRRNKVVGNPCPICRDHKLHVDFRNVKLLEQFVCAHTGIIFYAPYTGVCVKQHKRLTQAIQKARDHGLLIYHIPQVEPRDLDFSTSHGAVSATPPAPTLVSGDPWYPWYNWKQPPERELSRLRRLYQGHLQEESGPPPESMPKMPPRTPAEASSTGQTGPQSAL |
| Product Form |
Lyophilized powder |
| Tags |
N-terminal His-IF2DI Tag; N-terminal GST Tag |
| Type |
Recombinant Protein |
| Applications |
Western Blot; ELISA |
| Storage |
Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
Target
| Alternative Names |
MRPS18B; 28S ribosomal protein S18b; MRP-S18-b; Mrps18-b; MRP-S18-2 |
| Gene ID |
28973 |
| UniProt ID |
Q9Y676 |
| Location |
Mitochondrion |
| Introduction |
The MRPS18B protein is uniquely localized within the mitochondria, where it plays a pivotal role in facilitating the assembly and operation of the mitochondrial ribosome. Essential for sustaining efficient energy production via oxidative phosphorylation, the MRPS18B protein is indispensable for maintaining metabolic homeostasis. Alterations, including mutations or deletions, in the MRPS18B gene have been associated with a diverse array of mitochondrial disorders, notably including combined oxidative phosphorylation deficiencies. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.