This product is a recombinant human RPS6KB1 protein with N-terminal His tag. It is availible for SDS-PAGE, WB and positive control.
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Lot Number| This product is a recombinant human RPS6KB1 protein with N-terminal His tag. It is availible for SDS-PAGE, WB and positive control. |
| Species Reactivity | Human |
| Molecule Mass | 33 kDa |
| Purity | >90% determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Expression Host | E.coli |
| Formulation | PBS, pH 7.4, containing 0.01% SKL and 5% trehalose |
| Residues | 91-352aa |
| Sequence | FELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIY AFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQG HVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFF |
| Product Form | Lyophilized powder |
| Tags | N-terminal His Tag |
| Type | Recombinant Protein |
| Applications | SDS-PAGE; WB; Positive Control |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Alternative Names | PS6K; S6K; S6K1; STK14A; p70(S6K)-alpha; p70-S6K; p70-alpha; P70-S6 Kinase 1; 70 kDa ribosomal protein S6 kinase 1 |
| Gene ID | 6198 |
| UniProt ID | P23443 |
| Location | Nucleus; Cytoplasm |
| Introduction | RPS6KB1 is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. Studies have shown that RPS6KB1 activity plays an active role in increased autophagy. In addition, RPS6KB1 leads to increased protein synthesis and cell proliferation. |